CALL FOR PAPERS Integrative and Translational Physiology: Integrative Aspects of Energy Homeostasis and Metabolic Diseases Effects of weight loss and leptin on skeletal muscle in human subjects

نویسندگان

  • Kenneth M. Baldwin
  • Denis R. Joanisse
  • Fadia Haddad
  • Rochelle L. Goldsmith
  • Dympna Gallagher
  • Katherine H. Pavlovich
  • Elisabeth L. Shamoon
  • Rudolph L. Leibel
  • Michael Rosenbaum
چکیده

Kenneth M. Baldwin,* Denis R. Joanisse,* Fadia Haddad, Rochelle L. Goldsmith, Dympna Gallagher, Katherine H. Pavlovich, Elisabeth L. Shamoon, Rudolph L. Leibel, and Michael Rosenbaum Department of Physiology and Biophysics, School of Medicine, University of California at Irvine, Irvine, California; Division of Kinesiology, Laval University, Quebec, Canada; Division of Exercise Physiology; Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York; Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York; and Division of Molecular Genetics, Departments of Pediatrics and Medicine, Columbia University, New York, New York

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Effects of weight loss and leptin on skeletal muscle in human subjects.

Maintenance of a 10% or greater reduced body weight results in decreases in the energy cost of low levels of physical activity beyond those attributable to the altered body weight. These changes in nonresting energy expenditure are due mainly to increased skeletal muscle work efficiency following weight loss and are reversed by the administration of the adipocyte-derived hormone leptin. We have...

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تاریخ انتشار 2011